Application

Immunohistochemistry (preferred fixatives are acetone and alcohols)

Immunocytochemistry

Immunoprecipitation

FACS Analysis

ELISA

Radioimmunoassay

Biological Activity: MAB16983 inhibits CS-1 and VCAM binding.

Optimal working dilutions must be determined by end user.

Anti-Integrin α4 Antibody, clone P1H4 detects level of Integrin α4 & has been published & validated for use in ELISA, FC, IP, IC, IH.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Sepharose is a registered trademark of Cytiva

Linkage

Replaces: 04-1131

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified immunoglobulin from Protein A Sepharose^® chromatography. Liquid in 0.02M PB, pH 7.6, 0.25M NaCl containing 0.01% sodium azide.

Format: Purified

Specificity

The involvement of integrins in vascular proliferation, adhesion, and wound repair and have been well-documented. The integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based upon the pairing abilities of the individual alpha and beta subunits. Monoclonal antibody MAB16983 was produced by immunization with human T lymphocytes. The antibody is reactive with integrin a4 from primate and human species.

Storage and Stability

Maintain at +2-8C.